A comparative study of multimodal magnetic resonance in the differential diagnosis of acquired immune deficiency syndrome related primary central nervous system lymphoma and infection
نویسندگان
چکیده
Abstract Background Patients with acquired immune deficiency syndrome (AIDS) often suffer from opportunistic infections and related primary central nervous system lymphoma (AR-PCNSL). Both diseases showed multiple ring enhancement lesions in conventional magnetic resonance (MR). It is very difficult to make the differential diagnosis. We aimed investigate whether multimodal MR (diffusion weighted imaging (DWI)/ apparent diffusion coefficient (ADC), 3D pseudo-continuous arterial spin labeling (3D-pCASL) susceptibility-weighted (SWI)) combined can differentiate AR-PCNSL infections. Methods This was a prospective study. recruited 19 AIDS patients who were divided into group (9 cases) infection (10 by pathological results. analyzed there statistical ( Fisher’s method) difference between two groups. could improve diagnosis of AR-PCNSL. Results The more likely involved paraventricular (0.020) corpus callosum (0.033) MR. In MR, low ADC value, p values 0.001. Infection inclined high 0.003. had signal intensity (grade 2–3) degree intratumoral susceptibility SWI (SWI-ITSS), sensitivity, specificity 88.9 70.0%. sequence DWI/ADC sensitivity 100.0%, 60.0%. SWI-ITSS 100 or improved Conclusion Multimodal distinguish infectious lesions. (DWI/ADC SWI-ITSS) value should be attached importance clinical work. When distinguishing toxoplasmosis tuberculoma, used obtain correct
منابع مشابه
Paradoxical central nervous system immune reconstitution syndrome in acquired immunodeficiency syndrome-related primary central nervous system lymphoma.
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ژورنال
عنوان ژورنال: BMC Infectious Diseases
سال: 2021
ISSN: ['1471-2334']
DOI: https://doi.org/10.1186/s12879-021-05779-4